Novel Methods to Improve the Efficiency of Radioimmunotherapy for Non-Hodgkin Lymphoma

New paper by NIIMA and CIP USERN interest groups

Radioimmunotherapy (RIT) is a novel strategy for treating non-Hodgkin lymphoma (NHL).
Several studies have shown the promising results of using RIT in NHL, which have led to FDA approval for two RIT agents in treating low grade NHL.
In this paper, novel methods that improve the efficiency of RIT and reduce its toxicity through various mechanisms are reviewed...

To read the full paper:
https://www.tandfonline.com/doi/abs/10.1080/08830185.2019.1588266?journalCode=iiri20

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Cancer Immunotherapy: The way to the Nobel Prize in Medicine

To read the full paper:
http://acta.tums.ac.ir/index.php/acta/article/view/7535

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Roles of Myeloid-Derived Suppressor Cells in Cancer Metastasis: Immunosuppression and Beyond

New paper by NIIMA, CIP, and BrCA USERN interest groups

Metastasis is the direst face of cancer, and it is not a feature solely dependent on cancer cells; however, a complex interaction between cancer cells and host causes this process.
Myeloid-derived suppressor cells (MDSCs) are key components of tumor microenvironment that favor cancer progression...

To read the full paper:
https://link.springer.com/article/10.1007%2Fs00005-018-0531-9

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🌐 CIMT Membership for FREE!

Association for Cancer Immunotherapy

🔹CIMT accepts applications of individuals active in the discovery and translation of cancer immunology and immunotherapy.

🔹Membership in the association is free and gives you the opportunity to:

🌀connect with a network of scientists, physicians, organizations, and institutes that actively work in the field of cancer immunotherapies
🌀participate in our working groups
🌀be eligible to serve on CIMT committees and in leadership roles

https://www.cimt.eu/membership

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PhD position in Homburg, Germany
Saarland University - Physiology Institute

PhD position (E13/2) in cellular & molecular immunology

🔹A young and motivated departrnent which focusses on deciphering immune cell function, particularly interested in investigating the effector function of Cytotoxic T lymphocytes which are an important part of the adaptive immune system and in the long term in immunotherapy for Cancer.

🔹You are a highly motivated student with a masters degree in biolory or related field, chemistry or pharmacy and someone who enjoys working in an intemational interdisciplinary team.
The position is available immediately and will be funded by the DFG.

🔹If you are interested in such a PhD position, contact:
Dr. Varsha Pattu 
Saarland University
Centre for Integrative Physiolory und Molecular Medicine Department
Cellular Neurophysiolory
e-mail: [email protected]

#PhD_position

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Cancer Research Institute Postdoctoral Fellowships

✅The Cancer Research Institute (CRI) provides funding to ensure that the most promising postdoctoral scientists receive the critical financial support and continued career training needed to pursue their lifesaving work.

✅CRI invites postdoctoral fellows working in both fundamental immunology and tumor immunology to apply for funding.

✅Fellows receive up to $175,500 over three years to cover the cost of salary, insurance, and other research-related expenses, such as travel to conferences and meetings.

✅For more information:
http://www.cancerresearch.org/scientists/fellowships-grants/post-doctoral-fellows/application-guidelines

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Clinic and Laboratory Integration Program

✅The Cancer Research Institute funds research aimed at furthering the development of immunological approaches to the diagnosis, treatment, and prevention of cancer. The Institute's mission is to bring effective immune system-based therapies to cancer patients sooner.

✅The Clinic and Laboratory Integration Program (CLIP) grants provide catalytic support for translational laboratory studies designed to answer new specific scientific questions that arise in the clinic, with special focus on improving immunotherapy for cancer patients.

✅CLIP grants provide up to $200,000 over a two-year period.

✅For more information:
http://www.cancerresearch.org/scientists/fellowships-grants/translational-research-grants/clip-application-guidelines

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iATLAS
CRI Awards Grant to Develop Powerful Genomic Data Resource for Cancer Immunotherapy Researchers

✅The CRI iAtlas database is the first comprehensive effort in immuno-oncology to address the recent National Cancer Moonshot Blue Ribbon Panel recommendation to establish a pan-cancer immune atlas that would help catalyze new research in cancer immunotherapy.

✅The CRI iAtlas will serve as a central knowledge base to capture data on the tumor microenvironment and its impact on anti-cancer immune responses. Data generated by the working group, which includes molecular profiling of over 10,000 tumors across 33 tumor types as well as a series of results on immune-tumor interaction and response mechanisms, will provide rich characterizations of the relationship between tumors and the immune microenvironment and its impact on patient outcomes:
https://www.cri-iatlas.org

✅For more information:
http://cancerresearch.org/news/2017/cri-awards-grant-to-develop-powerful-genomic-data

#Grant

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Comparison of the effects of adipose tissue mesenchymal stromal cell-derived exosomes with conditioned media on neutrophil function and apoptosis

New paper by USERN interest groups

🌀Mesenchymal stromal cells (MSCs)-derived exosomes and conditioned media (CM) increased neutrophil phagocytosis capacity.

🌀The MSC-CM augmented neutrophil reactive oxygen species (ROS) production, but it couldn’t decrease neutrophil apoptosis.

🌀MSC-xosomes could decrease neutrophil apoptosis.

🌀MSC-exosomes and CM may be useful for increasing immunity by improving neutrophil function and survival.

To read the full paper:
https://www.sciencedirect.com/science/article/pii/S1567576919306964?via%3Dihub

#Paper

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IL-17 and colorectal cancer: From carcinogenesis to treatment

New paper by USERN interest groups

🌀Interleukin-17 can promote colorectal cancer tumorigenesis by several pathways.

🌀Interleukin-17 is associated with metastasis and poor prognosis in colorectal cancer.

🌀Interleukin-17 is a protective cytokineagainst colorectal cancer.

🌀Interleukin-17 can be used as a diagnostic marker in colorectal cancer.

🌀Interleukin-17 has been a new target in treatment of colorectal cancer patients.

To read the full paper:
https://www.sciencedirect.com/science/article/abs/pii/S1043466619300092?via%3Dihub

#Paper

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USERN RESEARCH WEEK

🔹USERN SUMMER EVENT
🔹August 2019
🔹For more information and register:
https://docs.google.com/forms/d/e/1FAIpQLSfRTbSIU15Lb9tkyPSacghOW_85EiWj0UHiU-sYeyfxHdzy7w/viewform

#Workshop

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Post-doctoral position in Immunotherapy
The University of Houston

✅Postdoctoral position to investigate T-cell based therapies in collaboration with M.D. Anderson Cancer Center, funded by the CPRIT/DoD/NSF. The candidate needs to have prior documented experience in molecular biology and in working with immune cells. The successful candidate will work on a multi-disciplinary team involving engineers and clinicians.

✅ Education/Experience: A Ph.D. or MD/Ph.D. degree in a related field like molecular or cell biology is required. Experience with standard immunological assays like ELISA/ELISpot/Flow-cytometry is an advantage. Experience with viral transduction of immune cells is an advantage.

✅Please send CV and list of three references via email to [email protected]

#Postdoc_position

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Killer T Cell and Cancer Cell

Source: https://youtu.be/ntk8XsxVDi0

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Tumour Immunology and Immunotherapy

Source: https://youtu.be/K09xzIQ8zsg
Nature Reviews Cancer and Nature Reviews Immunology

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How does cancer immunotherapy work?

Source: https://youtu.be/CwaMZCu4kpI
MD Anderson Cancer Center

#Movie

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Immunology Wars: Monoclonal Antibodies

Source: https://youtu.be/5AXApBbj1ps
Nature Video

#Movie

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Tumor-Related Immune Checkpoints and The Development of Targeted Cancer Immunotherapies

Source: https://youtu.be/Nb3b5XfMgIM
OriGene

#Movie

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🏅 چهارمین کنگره بین المللی یوسرن و جشنواره جایزه یوسرن
۱۷ تا ۱۹ آبان ماه ۱۳۹۸
بوداپست، مجارستان

با افتخار به اطلاع میرساند که امسال بیش از ۱۰۰۰۰ دانشمند جوان نامزد شرکت در رقابت بین المللی جایزه یوسرن شدند، که از این میان بیش از ۲۰۰ کاندید نهایی در ۵ حیطه اصلی (علوم ریاضی، علوم فیزیکی و شیمی، علوم بیولوژی، علوم پزشکی و علوم اجتماعی) به دبیرخانه جشنواره ارسال شدند.
از این بین پس از داوری توسط بورد مشاورین، ۱۰ نامزد منتخب در هر حیطه معرفی شده اند.

سپاسگزار همراهیتان خواهیم بود اگر دقایقی از وقت خود را در اختیارمان قرار داده و از نگاه خود، به این نامزد ها امتیاز دهید 🙏

لینک فرم ثبت آرا:
http://shorturl.at/cnvW3

📌جهت آشنایی بیشتر با کنگره یوسرن:
https://userncongress.com/

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Memorial Sloan Kettering Cancer Center
Postdoctoral Fellow Adusumilli Lab

✅Memorial Sloan Kettering Cancer Center (MSK) is one of the world’s leading cancer centers. The blending of research with patient care is at the heart of everything they do.

✅They currently have a postdoctoral position available in the Adusumilli Laboratory at MSK:
https://www.mskcc.org/research-areas/labs/prasad-adusumilli
The laboratory’s focus is on developing and translating adoptive T-cell therapy for the treatment of cancers.

✅The ideal candidate will have a PhD or MD/PhD, with a background in immunology, a passion for science, and a desire to advance the understanding and treatment of cancer. 

✅Please send a CV, bibliography, brief statement of research interests, and names and details of three references to:
Krishna Tobon
Grants Coordinator/Editor
[email protected]

#Postdoc_position

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