Correct Answer - A
Ans. is 'a' i.e., Used in DLE
○ Clofazimine interferes with template function of DNA, is used in
lepra reaction and can cause icthyosis and hyperpigmentation

Ans. is 'a' i.e., Vancomycin
Vancomycin can cause red men syndrome

Correct Answer -C
Ans. is 'c' i.e., Pyrimethamine
○ Antimalarials that act on erythrocytic phase of schizogony are
called erythrocytic schizontocides. The available drugs can be
divided into?
1. Fast acting - Chloroquine, amodiaquine, quinine, mefloquine,
halofantrine, lumefantrine, atovaquone, artemisinin.
2. Slow acting - Pyrimethamine, Proguanil, sulfonamides
tetracyclines.

Correct Answer -D

Correct Answer -C
Ans. is 'c' i.e., It does not cause alopecia
Vincristine belongs to the plant alkaloid group of anticancer
* Useful for inducing remission in childhood ALL (not useful in
maintenance therapy)
* It can also be used for pediatric solid tumors (Wilm's tumor,
neuroblastoma, rhabdomyosarcoma) and lymphomas
* Prominent adverse effects?
* Peripheral neuropathy
Alopecia
SIADH

Correct Answer - A
Ans. is 'a' i.e., Inhibits mitotic spindle
Vinca alkaloids (vincristine) inhibit mitotic spindles by preventing
polymerization of tubulin

Correct Answer - B
Ans. is `b ' i.e., Cisplatin
○ Cisplatin is the most common culprit causing chemotherapy
induced nausea and vomiting, therefore cisplatin is given as slow i.v.
infusion(never bolus) to prevent vomiting

Correct Answer-A
Ans. is 'a' i.e. Cisplatin
Some nephrotoxic_agents which_ cause tubular necrosis.
○ Aminoglycosides Colistin
○
Methoxyfluranes ○ Sulfonamides
○ Amphotericin B
o Cyclosporine
○
Polymyxin
○ Tetracyclines
○ Cephaloridine ○ Intravenous immune globulin
Radioiodinated contrast A cetaminophenmedium
○ Cisplatin

Correct Answer-D
Ans. is 'd' i.e., Aminoglycosides