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🇬🇧 Case Report: Compassionate Application of Chlorine Dioxide-based Solution in a patient with Metastatic Prostate Cancer
Peer-reviewed article
Submitted: 26-08-2023
Revised: 31-10-2023
Accepted: 02-01-2024
Published: 03-01-2024
Editor: Dr. William Castillo González, https://orcid.org/0000-0003-3007-920X
Manuel Aparicio-Alonso
Centro Médico Jurica, Medical Direction and Healthcare Responsibility, Querétaro, México
https://orcid.org/0000-0002-0188-9871
VerĂłnica Torres-SolĂłrzano
Universidad Autónoma de Querétaro, Unit for Basic and Applied Microbiology. Querétaro, México
https://orcid.org/0009-0004-2204-3754
DOI: https://doi.org/10.56294/saludcyt2024699
Keywords: Chlorine dioxide solution, cancer, reactive oxygen species, case report
Abstract
Chlorine dioxide is a powerful and cost-effective oxidizing agent that has demonstrated anti-cancer activity both in vitro and in vivo. Its proposed mechanism involves the release of free radicals, which disrupt the delicate oxidative balance within cancer cells. In case report, the patient has voluntarily opted for compassionate chlorine dioxide therapy over continuing conventional chemotherapy and immunotherapy due to side effects and uncertain survival outcomes. The concentration of the chlorine dioxide solution was 1/100 times lower than the LOAEL threshold, ensuring that not compromise the patients' health. This is the first follow-up in patient diagnosed with metastatic prostate cancer, who shown tumor reduction at distant sites from the primary tumor with no side effects. This preliminary observation suggests that chlorine dioxide and its free radicals could be potential mediators of an anticancer response. However, it is imperative to emphasize the importance of conducting rigorous clinical trials to validate these initial findings.
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