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Nature重磅:揭开奶茶等高果糖饮食的促癌机制,肝脏将果糖代谢为脂质来“喂养”肿瘤

2024年12月4日,圣路易斯华盛顿大学的研究人员在国际顶尖学术期刊 Nature 上发表了题为:Dietary fructose enhances tumour growth indirectly via interorgan lipid transfer 的研究论文。

该研究表明,果糖有助于体内的肿瘤生长,但癌细胞通常缺乏代谢果糖所需的酶,该研究发现,肝脏将膳食果糖转化为脂质并进入血液,癌细胞利用这些脂质以制造细胞增殖所需的膜。也就是说,肝脏通过将膳食果糖转化为脂质,来为癌细胞的快速增殖供能,从而间接促进肿瘤生长。

果糖(Fructose),是一种单糖,是葡萄糖的同分异构体,也是饮食中仅次于葡萄糖的第二丰富的糖类。果糖具有口味好、甜度高、升糖指数低等优点,因此一度被认为是“健康糖”,被广泛添加到饮料和食品中,以提升口感。例如大家经常喝的奶茶等饮料中加的糖,就以果糖为主。

Nature

via Ziyu

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Nature重磅:揭开奶茶等高果糖饮食的促癌机制,肝脏将果糖代谢为脂质来“喂养”肿瘤

2024年12月4日,圣路易斯华盛顿大学的研究人员在国际顶尖学术期刊 Nature 上发表了题为:Dietary fructose enhances tumour growth indirectly via interorgan lipid transfer 的研究论文。

该研究表明,果糖有助于体内的肿瘤生长,但癌细胞通常缺乏代谢果糖所需的酶,该研究发现,肝脏将膳食果糖转化为脂质并进入血液,癌细胞利用这些脂质以制造细胞增殖所需的膜。也就是说,肝脏通过将膳食果糖转化为脂质,来为癌细胞的快速增殖供能,从而间接促进肿瘤生长。

果糖(Fructose),是一种单糖,是葡萄糖的同分异构体,也是饮食中仅次于葡萄糖的第二丰富的糖类。果糖具有口味好、甜度高、升糖指数低等优点,因此一度被认为是“健康糖”,被广泛添加到饮料和食品中,以提升口感。例如大家经常喝的奶茶等饮料中加的糖,就以果糖为主。

Nature

via Ziyu

📮投稿机器人 ☘️频道 🌸聊天

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