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Insulin Resistance and Cholesterol Changes
After eating a meal, carbohydrates are broken down into glucose by your digestive system. This glucose is then absorbed through the wall of your intestines into your bloodstream.
Once there, insulin—a hormone, made by your pancreas, that is the primary regulator of carbohydrate metabolism—brings glucose into various cells, so they have the energy to function and do their jobs. Insulin also blocks the breakdown of fat into fatty acids (lipolysis) within your body.1
Insulin resistance is when the cells become less responsive to this process. As a result, blood sugar eventually increases, which is why it's considered a precursor to pre-diabetes and type 2 diabetes.
Fats are also broken down within the body at an increased rate, and this ultimately leads to various cholesterol changes.2 Specifically, insulin resistance lowers HDL and raises triglycerides and LDL.2
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